High MDR1 expression in RA is associated with increased MMP-3 levels and use of bDMARDs: potential independence of JAK inhibitors from MDR1.
To identify patient-related factors linked to high multidrug resistance gene 1 (MDR1) expression in RA and assess whether MDR1 expression affects Janus kinase (JAK) inhibitor effectiveness. Synovial tissues were obtained from 53 RA patients undergoing total knee arthroplasty bet…