Romosozumab Achieves Consistent Lumbar Spine BMD Gains Across All BMI Categories: The Apparent Enhanced Response in Underweight Patients is a Mathematical Artifact of Percentage Change.
Body mass index (BMI) influences bone metabolism; however, its impact on romosozumab treatment response remains unclear. We investigated whether BMI independently predicts bone mineral density (BMD) response to romosozumab and re-examined the role of the outcome metric (absolute…