Soluble SIGLEC1 as a biomarker of disease activity in idiopathic inflammatory myopathies.
To investigate soluble circulating sialic acid-binding Ig-like lectin 1 (scSIGLEC1), a surrogate biomarker for type I IFN, as a novel biomarker for idiopathic inflammatory myopathies (IIM) disease activity. Patients enrolled in a Canadian multicentre cohort of IIM patients with…