Derivation of a new index to reduce the occurrence of multiple positivity in line immunoassay for myositis specific autoantibodies in inflammatory myopathies.
Myositis specific antibodies are clinically useful biomarkers in inflammatory myositis. Although immunoprecipitation is regarded as the gold standard, line immune assay (LIA) is widely used in practice. However, LIA is limited by multiple MSA positivity in up to 15% of patients,…