ANCA-Associated Vasculitides in Systemic Sclerosis: A Unique Clinical Overlap with Significant Implications for Treatment and Outcomes.
Systemic sclerosis (SSc) is an autoimmune disease characterized by autoantibody production, fibrosis, and vasculopathy. The coexistence of ANCA-associated vasculitides (AAV) in SSc is rare and poorly characterized, with limited data on the impact of treatments, particularly high…