Relevance of isolated IgM antiphospholipid antibodies in a longitudinal cohort of antiphospholipid syndrome.
IgM aCL and anti-β2 glycoprotein I (aβ2GPI) positivity have been downgraded in the current classification criteria for APS. We assessed the clinical relevance of IgM aPL in APS. A 5-year longitudinal study was conducted in 186 individuals: 54 aPL carriers, 83 with th…