The Effect of Intranasal Niclosamide on Nasal Symptoms in Patients with Anti‐Neutrophil Cytoplasmic Antibody‐Associated Vasculitis
Objective Ear, nose and throat (ENT) manifestations are common in ANCA‐associated vasculitis (AAV). There is unmet need for drugs to target these manifestations. Granuloma formation is characteristic of proteinase 3 (PR3)‐AAV. In a zebrafish model, niclosamide inhibits PR3‐induc…