Certolizumab Inhibits Radiographic Progression in Patients with Early Rheumatoid Arthritis and High Rheumatoid Factor Levels: A Pooled, Post‑Hoc Analysis of the Phase 3 C‑EARLY and C‑OPERA Trials
OBJECTIVE: To assess radiographic progression in patients with early rheumatoid arthritis (RA) and poor prognostic factors treated with certolizumab pegol (CZP)+methotrexate (MTX) versus placebo (PBO)+MTX, stratified by rheumatoid factor (RF) level. METHODS: In a pooled, post‑ho…