The influence of CYP3A5 genotype on tacrolimus pharmacokinetics in patients with SLE.
Cytochrome P450 3A5 (CYP3A5) gene polymorphisms affect tacrolimus (TAC) pharmacokinetics. However, their impact on the clinical management of SLE remains unclear. This study aims to investigate the influence of CYP3A5 gene polymorphisms on pharmacokinetics of TAC and clinical ou…