Transcriptome analysis unveils Th1 cell cycle signature as a distinctive feature of mixed connective tissue disease.
Mixed connective tissue disease (MCTD) is characterized by positivity for anti-U1-RNP antibodies and a combination of symptoms of systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and inflammatory myositis (IIM). The aim of this study was to elucidate the similaritie…