Single-cell profiling reveals CCL5Hi GZMAHi effector memory CD8 T cell association to oligoarticular juvenile idiopathic arthritis.
Oligoarticular juvenile idiopathic arthritis (oligo JIA) is the most common JIA subtype and is often complicated by uveitis, a potentially sight-threatening comorbidity. Despite its prevalence, the immunopathogenic mechanisms underlying oligo JIA and its extra-articular manifest…