Single‐cell RNA sequencing informs precision targeting of monogenic lupus associated with IKZF1 haploinsufficiency
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently kn…